When is the best time of the day to take CBD oil?

There’s no definitive answer to this question.

Most people tend to work out their daily dose and then split it into two amounts and take one morning, one night.

However, CBD is biphasic which means that at smaller doses it can be a bit stimulating and at higher doses somewhat sedating.

So, some people who use it for sleep, prefer to take the whole dose night for the sedating effect.

Will CBD oil stop working due to tolerance?

In order to understand CBD tolerance, and how to avoid it, it helps to know what is being avoided.

It’s great to throw a word like ‘tolerance’ around, and its basic meaning is understood by most, even if the functional understanding of how it happens is not.

Sure, we know that the body essentially acclimates to the substance, thereby not responding to it in the same way, but what does this mean?

In terms of pharmacodynamics (how a substance effects the body), tolerance occurs at the cellular level, when a substance is repeatedly used, leading to less response by the cell.

Most of the time this is from a large amount of a substance consistently binding to the same receptor until the receptor becomes desensitized to the substance.

Another form of pharmacodynamic tolerance is when the number of receptors is reduced, which means a change in firing rate and action potential.

Tolerance happens in another way as well, pharmacokinetic tolerance, which explains how the body effects the substance.

Pharmacokinetics deals with how the substance is treated by the body through absorption, distribution, metabolism, and excretion.

This kind of tolerance refers to the decreased amount of the substance that’s capable of reaching reactor sites. This is often caused by increased enzyme action to break down the substance before it can do what its supposed to.

What about CBD tolerance?

The study Cannabidiol (CBD) Tolerance in Children and Adults With Treatment-resistant Epilepsy was published in 2021, and gives a view of the subject.

The study lasted three years and looked at tolerance among 92 treatment-resistant epileptic patients.

In this study, tolerance was defined as either the need to increase dosage because of reduced efficacy by at least 30%, or with a 30% or more increase in symptoms with at least three months treatment, and no increase in medication.

Tolerance to the CBD was found in only 25% of the population, starting at approximately 7.3 months. 

How to Avoid CBD Tolerance?

 The main way of avoiding tolerance, or lessening it when if you happen to be one of the 25%, is simply to take a break.

It was found that after a break of just two days CBD receptors become more active again.


A good rule of thumb, is if you find yourself not feeling all the effects, take a few days off, let your tolerance lower and start taking it again. 

Do you sell a CBD oil salve or lotion?

No, because it’s super-easy and convenient to make your own at home using our powerful and cost-effective CBD oil.

Here are the instructions:

Make sure to note three main aspects, and you can enjoy a DIY version within minutes.

1. Choosing Your Base

When making a base, there are many different ingredients to choose from, such as:

Shea butter
Cocoa butter
Coconut oil
Jojoba oil
Olive oil
Or any store-bought lotions.

Each one comes with its own benefits and will provide a different consistency. Beeswax, for example, is more frequently used to create a harder salve, as opposed to a softer lotion.

A salve will be an ideal choice if you intend on applying the topical to a small, contained area.

However, a lotion will be easier to spread across a larger area.

You can combine however many ingredients you feel are necessary to make you base. For example, coconut oil and beeswax may provide a balanced consistency that also massages the skin.

Alternatively, if you’re on a budget, simply incorporating your chosen CBD oil with a store-bought lotion will serve your needs properly.

Be sure to check the ingredients list, however, and ensure your branded lotion has a low water content. Water and oil don’t mix, after all, and this can lead to a topical that doesn’t spread evenly.

2. Choosing your CBD Oil

When making a topical, you’re going to use anywhere from 300 to 600 milligrams of cannabidiol oil so you will want to choose a concentrated oil suitable for this purpose.

3. Measure Properly

Measuring becomes extremely important, as you want to balance the amount of base with the amount of CBD oil, according to how much is needed each time.

When making a salve, you’ll be using less total ingredients than with a lotion. This is because salves are more condensed and deliver focused results, so you can incorporate less beeswax but the same amount of CBD oil.

If you decide to make your own salve, add the CBD oil before taking it off the heat. If you decided to buy a pre-made salve, remove it from its container and heat it either on low in the microwave or in a pot on the stove at low heat.

Add 400mg of CBD oil for every 60ml of salve.

We would recommend using either the Canntica 2500mg or the 5000mg best value for this because they are the most concentrated at 4mg per drop.

If you use either of these products, you’ll be using 100 drops (4 x 100 = 400mg) for every 60ml of salve.

For a lotion topical, you’ll have more to use, but you’ll need a greater amount to get the same affect.

Since lotion is already easy to mix, simply add 600mg of CBD oil for every one cup of lotion and stir until completely dispersed into the lotion.

Again, we would recommend using either the Canntica 2500mg or the 5000mg best value for this because they are the most concentrated at 4mg per drop.

If you use either of these products, you’ll be using 150 drops (4 x 150 = 600mg) for every one cup of lotion.

If you decide later that your topical is too strong or too weak, you can add more base or CBD oil to it as needed. Salves will need to be warmed up before adding more CBD oil, as they tend to harden and will resist the oil.

Now you can use CBD oil in two ways: systemically by placing drops under the tongue and topically via your salve or lotion.

How much do you charge for shipping?

  • All orders for Canntica are shipped to you discreetly in unmarked packaging.
  • All orders are sent via US Postal Service Priority Mail with tracking within the US (2 – 3 day service) and by Air Mail outside the US (approx 10 – 14 day service). 
  • If you are in Australia or New Zealand, your order will be sent by Express Post (approx 2 – 4 day service) for FREE.
  • We have many clients in Australia and none have reported any problems receiving their orders.
  • All orders are shipped complete with lab-sealed CBD Oil.
  • All orders are triple checked for accuracy before shipping.

Is CBD oil addictive?

No. CBD oil such as Canntica is not addictive, nor can it make an individual feel “stoned.”

Marijuana is well-known as an addictive. However, confusion often surrounds hemp and cannabidiol (CBD), which are related to marijuana but do not contain the psychoactive component that characterizes marijuana.

In fact, CBD actually counteracts the psychoactive influence of THC and has demonstrated anti-psychotic effects in schizophrenia patients.

The concentration of THC in marijuana is high enough to potentially cause addiction. 

However, Canntica contains zero THC and there can’t create an addiction.

Individuals who wish to treat medical ailments or symptoms with herbal medicine often want the benefits of using CBD such as Canntica. 

What is the difference between your CBD oil sizes?

All of the Canntica CBD oil bottles contain either 30ml (1oz) or 60ml (2oz) of oil and have two components: CBD oil and hemp seed oil.  The only difference is the concentration of these oils.  For example, the 2500mg and 5000mg bottles contains a very large proportion of CBD oil so it is very concentrated at 4mg of CBD per drop.  On the other end of the spectrum, the 500mg starter bottle contains much more of the hemp seed oil and the least amount of CBD oil, only 0.83mg per drop.  This range of concentrations allows consumers to choose a product that suits their use and their budget. 

Finally, it is very easy to transition from one product to another by simply adjusting how many drops are used and therefore how long a particular product will last.  For example: A) If you want to take 15mg per day and your product is the 500mg bottle and has 0.83mg of CBD per drop, you would take 18 drops. (18 x 0.83 = 15mg)  B) If you want to take 15mg per day and your product is the 1500mg bottle and has 2.5mg per drop, you would take 6 drops. (2.5 x 6 = 15mg) C) If you want to take 15mg per day and your product is the 2500mg or 5000mg bottle and has 4mg per drop, you would take 4 drops. (4 x 4 = 16mg).

What can I do to boost the effectiveness of CBD oil if I don’t think it is working?

The first thing would be to try increasing the dose.  Everyone is different and body weight also has an effect ie, a large man would need to use more than a small woman.  The second thing would be to ensure that you have enough essential fatty acids in your diet, omega 3 in particular.  When you take CBD oil, CBD and cannabinoids in the oil interact with the receptors in your endocannabinoid system, just like cannabinoids synthesized naturally inside your body because the chemical structure is essentially the same. They may also be modulated in their action by the specialized enzymes that can break them down (degrade them). It is this interaction with your endocannabinoid system that allows the cannabinoids in CBD oil to perform their magic. It turns out that omega 3 plays a very critical role in maintaining proper functioning of your endocannabinoid system. This cannot be overemphasized enough so pay very close attention to this message: if you do not get enough omega 3 in your diet or through supplementation, you will not receive as great a benefit from taking CBD oil! Here are just a few of the ways omega 3 helps maintain your endocannabinoid system: (1) Keeps the receptors healthy and functioning properly. (2) Helps you grow more receptors when you need them. (3) Helps repair receptors. (4) Helps synthesize cannabinoids within the body. You need this even if you are supplementing with CBD oil! (5) Helps keep your omega 6 to omega 3 ratio low. You need this to maintain healthy membranes that can support the receptors. (6) Helps create one type of cannabinoid out of another type as needed. (7) Helps create the enzymes needed to produce or degrade cannabinoids as needed to regulate the whole system.  So, in summary, if you don’t think you are getting enough omega 3 in your diet, you may need to supplement with, for example, a high quality fish oil.